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11 Jul

Cancer 101: Ex Smokers can Lower Their Risk for Lung Cancer

Posted on 2010 under Coach Quit Blogs | 5 Comments

Vitamins and L-Methionine Cut Lung Cancer Risk 50% Study Suggests

Reference Volume 303, No. 23, June 16th 2010, JAMA

Researchers findings: “  Serum levels of vitamin B6 and methionine were inversely associated with risk of lung cancer”.

In a study of 519,000 people (of whom  385,000 gave blood samples)  from 10 countries between 1992 and 2000, there was a significant finding. All participants were 35-79.

The group was separated into three groups:

Never smoked , Former Smokers, and Current smokers. The calculations for the study were done at the 95% confidence level.

Higher levels of B-6 was inversely related with lung cancer occurrences in the Never Smoked, Former Smoker, and Current Smoker groups. Suggesting strongly that higher B-6 levels in the blood deter lung cancer in some yet unknown way.

It was also found that the amino acid L-Methionine also had an effect. Higher levels of L-Methionine in the blood was related to lower incidences of lung cancer in the following groups. Never Smoked, Former Smoker, Current Smoker.

A lower rate for lung cancer was found for the vitamin Folate. But the effect was found only in the Former Smoker, and Current Smoker groups. There was no seen affect in the Never Smoked group.

The average minimum amount of the effect was around 50%.

What can we learn from this study?

This seems to be a large enough study over a large enough segment of time, and over several countries. These factors rule out variations due to locale, some pre-disease process, a wide range of age (35-79) and over a variety of researchers.

I believe that especially former smokers and current smokers could gain by utilizing the basic conclusions of this study, but with a caveat. Smokers and former smokers should make sure that they get an adequate amount of the B vitamins, particularly B-6, and B-9. In addition it would not hurt to make sure to get the L-Methionine amino acid. After all methionine is “essential”, that means it is needed by the body but not manufactured in the body. So, you need to deliberately go out and get it.

Here is the caveat: Don’t take huge amounts of these as supplements.

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Paul Brennan, one of the researchers of the study in the International Agency for Research on Cancer in Lyon, France said “We found that vitamin B6 and methionine are strongly associated with reducing lung cancer risk in people who never smoked, those who quit, and current smokers.”

50 percent reduction in lung cancer

“Our results suggest that above-median serum measures of both B6 and methionine, assessed on average five years prior to disease onset, are associated with a reduction of at least 50 percent on the risk of developing lung cancer. An additional association for serum levels of folate was present, that when combined with B6 and methionine, was associated with a two-thirds lower risk of lung cancer,” said Brennan.

Click HERE for JAMA article

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About Author

Don Muller created Coach Quit out of his own very real need to quit smoking. Although he had tried to quit smoking before, unsuccessfully, he had a new motivation. He was about to become a father, and he had just recently realized that smoking around your kids can give them life long illnesses like asthma. He could not imagine what it would be like to bring a child into this world, only to make her live a life of illness. So, he set about trying to understand why he couldn't quit smoking even though he wanted to. So, he analyzed ever detail of what a quit smoking should be, and then put the parts of the puzzle together for himself. He tried it once, because he quit the first time. He had taken away the problems that made it difficult to quit. He has not lit a cigarette since 1992 and never had the desire or need. He attributes that, to the constant "saying no" to cigarettes in various ways that are included in the Coach Quit system. His Doctor asked him to share the system, and that is how Coach Quit came about.